A prospective study of Green Tea and panax Ginseng against mutagens & carcinogens produced during Thermolyzed Meat and Fish
Osfor, M. M. H.; A. El-Ashi; M. El-Madbouly; Mona. S. zaki*; and Doaa Negm
Department of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia
* 'Department of Hydrobiology, National Research Center. Cairo, Egypt
Abstract: Effect of thermolyzed (ultra heated) Meat and fish on the nutritional, biochemical, histological, and hematological parameters as well as aberrations and sperm abnormalities was investigated in male albino rats. Animals were divided into two main groups: Meat group and Fish group. Each group was divides into six subgroups: G-I was fed the basal diet containing more than 12% dry frozen meat, G-II & G-III were fed the basal diet of G-I plus 5% of Green Tea and Panax Ginseng respectively. G-IV was fed the basal diet containing more than 12% Thermolyzed Meat, while, G-V & G-VI were fed the basal diet of G-IV plus 5% of Green Tea and Panax ginseng respectively. The same classification was done for the fish groups. It was found that the terminal body weight was increased non-significantly in all rat groups until the fifth week, and then decreased non-significantly until the end of the experimental periods (8 weeks). No effect on serum cholesterol, triglycerides, total lipids and glucose levels was found. On the other hand, significant values of both hepatic and renal function parameters were obtained among ultra heated meat and fish treated animals. Numerous histological alterations, particularly in the liver, were also observed. Moreover, anemia, leukocytosis, neutophilia, lymphocytosis and monocytosis were seen. Furthermore, chromosomes and sperms were adversely affected in such animals fed diet contained ultra heated meat and fish. The protective role of green tea and panax ginseng were observed in all biochemical, histological, and hematological parameters. In addition, improvement in chromosomal aberration and sperm abnormalities was also noticed.
[Osfor, M. M. H.; A. El-Ashi; M. El-Madbouly; Mona. S. zaki; and Doaa Negm. A prospective study of Green Tea and panax Ginseng against mutagens & carcinogens produced during Thermolyzed Meat and Fish. Life Sci J 2013;10(1):1754-1765]. (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Ultra heated meat and fish, Green Tea, Panax ginseng, Albino rats.