Analysis of clinical application of arsenic-free deactivating agent-Depulpin
Department of stomatology,the First Affiliated Huaian Hospital of Nanjing Medical Universical,Jiangsu,Huaian 223300,CHINA
Abstract: Objective: To investigate the clinical application effect and adverse reaction of arsenic-free deactivating agent-Depulpin. Methods: 536 teeth of 536 patients are divided into diferrent groups according to admission order, thery are Group A covering 180 cases and 180 teeth, Group B covering 178 cases and 178 teeth, Group C covering 178 cases and 178 teeth. They are administered with arsenic-free deactivating agent( Depulpin),arsenic deactivating agent and paraformaldehyde devitalizing agent respectively, then the results of them will be compared and analysed. Results ：The results shows that the effective rate for Depulpin group is 88.9%, that for arsenic deactivating agent group is 84.8%, that for paraformaldehyde devitalizing agent group is 78.7％. Upon chi-squared test, the comparison of ache effect between Group A and Group C is of non-statistical significance[ P = 0.066], the differences between group A and group B (P = 0.033) and group B and group C are of statistical significance(P = 0.038), which show that the application of arsenic inactivating agent may enhance pain response. Conclusion: Depulpin as a new arsenic-free deactivating agent is a kind of favorable pulp devitalizer due to its inactivation action and little toxicity.
[ZHU Zhen-ya. Analysis of clinical application of arsenic-free deactivating agent-Depulpin. Life Sci J2013;10(1):2858-2860] (ISSN:1097-8135). http://www.lifesciencesite.com.
[Keywords] pulp devitalizer; Depulpin; arsenic deactivating agent; paraformaldehyde devitalizing agent.