Antioxidant and anticancer activities of water and ethanol extracts obtained from Sasa quelpaertensis Nakai
Ji Young Kim §,1, Jung Hyun Kim §,2, Ji Hee Byun §,1, Ji Hye Kim 1, Youn Ji Lee 1, Soon Jae Im 1, Dong-Sun Lee 1,4, Seo Hyun Moon 3, Min Young Kim 1,4,*
1. Laboratory of Pharmacology and Toxicology, Faculty of Biotechnology, College of Applied Life Science,Jeju National University, Jeju 690-756, Republic of Korea
2. Department of Tourism and Food Service Cuisine, Cheju Tourism College, Jeju 695-900, Republic of Korea
3. DNA Forensic Center, National Forensic Service, Seoul 158-707, Republic of Korea
4. Subtropical Horticulture Research Institute, Jeju National University, Jeju 690-756, Republic of Korea
§. Contributed equally
Abstract: Antioxidant activities of Sasa quelpaertensis Nakai leaf extracts using two different solvents (water and ethanol) were determined by using in vitro antioxidant models including 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical, hydrogen peroxide and nitric oxide scavenging activities, and ferrous chelating and reducing power activities. Both extracts were shown to be antioxidants; however, ethanol extract exhibited higher antioxidant activity than that of water extract. The total phenolic and flavonoid contents of Sasa quelpaertensis Nakai leaf extract was positively correlated with the antioxidant activity. Significantly, the ethanol extract exerted the most potent cytotoxicity activity against human colon cancer HCT116 cells.
[Ji Young Kim, Jung Hyun Kim, Ji Hee Byun, Ji Hye Kim, Youn Ji Lee, Soon Jae Im, Dong-Sun Lee, Seo Hyun Moon, Min Young Kim. Antioxidant and anticancer activities of water and ethanol extracts obtained fromSasa quelpaertensis Nakai. Life Sci J 2013;10(1):1250-1254] (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Sasa quelpaertensis Nakai; antioxidant and anticancer potentials