Dexamethasone in prevention of respiratory morbidity in elective caesarean section in term fetus. A randomized control trial
1Ahmed Rushdi Ammar,1Noha Hamed Rabei and 2Hamdi Ahmed Gad
1Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Egypt.
2Resident of Obstetrics and Gynecology, Suhag Hospital
Abstract: Introduction: Babies born at term by elective caesarean section (CS) and before onset of labor are more likely to develop respiratory complications than babies born vaginally. In developing countries resources are scarce and it is difficult to provide expensive treatments as neonatal care. Aim of the Work: To assess the effect of prophylactic dexamethasone administration before elective cesarean section at term in reducing neonatal respiratory complications. Patients and methods: 600 women were included in the study and were planned to have elective caesarean section. 300 received dexamethasone 12 mg twice, 12 hours apart 48 hours before delivery. 300 patients were the control group. The outcomes were: incidence of admission to neonatal intensive care unit (NICU), incidence of transient tachypnea of neoborn (TTN), the incidence of respiratory distress syndrome (RDS) and the need for mechanical ventilation. Results: There was a highly significant difference between cases and controls as regard TTN and admission to NICU. There was a decrease in the incidence of RDS and the need for mechanical ventilation but with no significant differences. Conclusion: Antenatal dexamethasone is effective in reducing neonatal respiratory morbidity and admission to NICU.
[A.El-Taher, M. El-Hagary, M. Emam-Ismail, F. A. El-Saied and Fadl A. Elgendy. Dexamethasone in prevention of respiratory morbidity in elective caesarean section in term fetus. A randomized control trial. J Am Sci2013;9(6):286-289]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 33
Key words: dexamethasone, elective cesarean section, respiratory morbidity Full Text 33