Clostridium perfringens Disease
1Nagwa, Ata, 1Eman A. Khairy ,1Sohad M. Dorgham and 2Mona S, Zaki
1Dept.Microbiology and immunology, National Research Centre, Giza, Egypt
2Dept.Hydrobiology, National Research Centre, Giza, Egypt
Abstract: C. perfringens (Clostridium perfringens) is a pathogen whose infects human and animals. In spite of its potential danger as an infectious agent, avirulent forms of bacillus can be found in many different habitats, such as the normal flora of human gastrointestinal (GI) tract, and environment, such as sewage and soil. Several common diseases associated with C. perfringens were recorded such as food-poisoning, gas gangrene, necrotic enteritis and many veterinary diseases. The trouble starts when the balance of bacteria in the gut is disrupted, giving C. perfringens a chance to proliferate unchecked. It may contaminate soil, animal feed and litter, or be transmitted directly from infected to healthy animals. C. perfringens related livestock infections have been reported in most parts of the world. Once an animal contracts a disease caused by C. perfringens it’s often too late to do anything about it, Death comes quickly and violently. The most practical way to handle perfringens-related illnesses in animals is to prevent them in the first place. The present literature review of the diagnosis, type determination of major lethal toxins and diseases caused by C. perfringens.
[Nagwa, Ata, Eman A. Khairy, Sohad M. Dorgham and Mona S, Zaki. Clostridium perfringens Disease. Life Sci J 2013;10(1):1599-1602] (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Key words: C. perfringens; C. perfringens toxins; food poisoning; necrotic enteritis.