Evaluation of Positive Culture during the Initial Healing of Penetrating Ocular Trauma
Bahman Sharifi 1, 2, Hamid Reza Ghaffarian Shirazi2, 3*, Seyyed Hossein Malek-Hosseini1,2, Esmat Afzalian 2
1 - Department of Ophthalmology, School of Medicine, Yasuj University of Medical Sciences.
2 - Cellular and Molecular research center, Yasuj University of Medical Sciences, Yasuj, I. R. Iran.
3- School of Public Health, Tehran University of Medical Sciences, Tehran, I. R. Iran.
*Corresponding Author: email@example.com
Abstract: Endophthalmitis is usually a devastating complication, followed by penetrating eye injuries that oftencauses severe loss of vision. Bacterial and fungal cultures were used to evaluate the primary healing of penetrating oculartrauma which is positive in the diagnosis of endophthalmitis. Materials and Methods: This prospective study wasperformed on 105 patients with penetrating eye trauma during the initial healing, in which, bacterial and fungal cultureswere obtained from wounds, vitreous, aqueous humor and intraocular foreign body. The positive culture rate ofendophthalmitis was compared in eyes with and without clinical diagnoses. In addition, factors affecting in causingpositive culture and endophthalmitis was studied. Results. About 24% of patients had positive culture of wound,vitreous, aqueous humor and the intraocular foreign body. Thirteen percent (13%) of clinically diagnosedendophthalmitis were developed during treatment. 50% of patients enjoyed positive culture with clinical diagnosis ofendophthalmitis. Despite positive cultures, 18 eyes (20%) had not any sign of endophthalmitis. Sclera rupture wasobserved in 25 patients with 48% positive culture and also in 20 patients with 25% negative culture. 32% of 25 patientswith the positive culture enjoyed iris prolapse and 80 patients with 11% negative culture enjoyed iris involvement. Patients with 40% positive culture and also patients with 10% negative culture had a foreign body in the eye. Of 14cases of positive culture of pathogenic organisms, 43% faced endophthalmitis. Discussion. Despite the positivebacterial cultures during primary healing of penetrating ocular trauma, clinical infection is not created. So, bacterial cultureduring the initial healing is not helpful in diagnosis of the next endophthalmitis. Iris involvement, sclera laceration andintraocular foreign body increases possibility of positive bacterial cultures during the initial healing significantly.Possibility of risk of endophthalmitis is increased in case of entrance of microorganisms with more virulence duringpenetrating ocular trauma to the eye.
[Sharifi B, Ghafarian Shirazi H.R, Saniee F, Delaviz H. Evaluation of Positive Culture during the Initial Healing ofPenetrating Ocular Trauma. Life Sci J 2013;10(7s):539-544] (ISSN:1097-8135). http://www.lifesciencesite.com. 84