Antiglycation, Cytotoxicity and Phytotoxicity of Crude Extract of Sonchus eruca
Zia Muhammad1, Shabir Ahmad1, Riaz Ullah2, and Umar Nishan3 and Tahir Muhammad4
1Department of Chemistry, Kohat University of Science and Technology Kohat, Kohat -26000, N.W.F.P, Pakistan
2Government Degree College Ara Khel FR Kohat KPK Pakistan
3International Center for Chemical and Biological Sciences, HEJ RIC, University of Karachi, Karachi-75270, Pakistan.
4Department of Chemistry, Gomal University, Dera Ismail Khan, KPK, Pakistan.
Abstract Three fractions methanol (SEM), ethylacetate (SEE) and butanol (SEB) of Sonchus eruca were subjected to test against antiglycation, cytoxicity and phytotoxicity. In case of antiglycationbioassay, methanol fraction showed highest inhibitory activity 65.60 % fallowed by ethyl acetate 45.20 % and butanol 20.40 %. All three fractions did not show any significant cytotoxic activity. The ethyl acetate fraction exhibited significant phytotoxic activity.
[Zia Muhammad, Shabir Ahmad, Riaz Ullah, and Umar Nishan and Tahir Muhammad. Antiglycation, Cytotoxicity and Phytotoxicity of Crude Extract of Sonchus eruca. Life Sci J 2013;10(1):2716-2718] (ISSN:1097-8135). http://www.lifesciencesite.com. 3
Key words: Sonchus eruca, antiglycation, Cytotoxicity, Phytotoxicity