Antioxidant activity of celery in vitro and vivo
Amnah, M. A .Alsuhaibani
Nutrition and Food Sciences Dept, Home Economic Collage, Princess Nora Bint Abdul Rahman -University, Riyadh, Saudi Arabia. email@example.com
Abstract: The objective of this work was to investigate the main antioxidant components of celery and study the antioxidant effect of celery extract in vitro and in vivo in rats. Oxidative stability of celery extract was determined by estimation of peroxide value. Celery extract and BHT at level 400 ppm effectively inhibited the increase in peroxide value especially for a period of 32 hrs of heating. Forty Sprague Dawley adult male rats classified into control (-ve) and four groups which received 200 mg/kg body weight of potassium bromate in drinking water for 30 days to induce renal injury and reclassified into positive control (untreated) and treated rat groups that werecelery powder, 2.5celery extract and 5 celery extract groups. Results clearly revealed that 2.5 celery extract and 5 celery extract groups showed normal body weight gain, food intake, protein intake and protein efficiency ratio but showed lower food efficiency ratio compared to control (-ve) rat group. Celery powder rat group showed highly significant increase in serum creatinine, urea, ALT and nitric oxide (NO) but showed significant lower in serum antioxidant enzymes and also kidney superoxide dismutase (SOD), compared to control (-ve) rat group.2.5celery extract group showed significant lower in SOD and GPX while 2.5 celery extract and 5 celery extractgroups showed normal in renal function0 parameters and the values of kidney antioxidant enzymes compared to control (-ve) rat group.
[Amnah, M. A .Alsuhaibani. Antioxidant activity of celery in vitro and vivo. J Am Sci 2013;9(6):459-465]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 57
Keywords: Celery - BHT- potassium bromate - rats. Full Text 57