Management of Pos
Management of Postpartum Interval of Nubian goats with PGF2α and GnRH
Adil Salim Elsheikh 1, 2, Nawal Nour Eldaim Omer1, Abdulrahman Mohamed Alqurashi 2
1 Department of Reproduction and Obstetrics Faculty of Veterinary Medicine University
of Khartoum P.O Box 32.
2Department of Applied Medical Sciences, Community College, Najran University, Saudi Arabia
Abstract:In this study two experiments were designed to examine the effects of prostaglandin (PGF2α) and gonadotropin releasing hormone (GnRH) on the length of postpartum interval to first oestrous (PPI) and progesterone (P4) profile of postpartum (p.p.) Nubian goats. In experiment I the PPI and P4 profile of p.p. Nubian goats treated with PGF2α were compared with untreated control. Seventeen p.p. Nubian goats (2 to3 years old) were divided into 4 groups. Groups I (n = 4) was intramuscularly injected (i.m) with 125 µg of PGF2α on day 7 p.p., group II (n = 4) was injected on day 15 p.p., group III (n = 4) was injected on day 21 p.p. and group IV (n = 5) was not injected and served as controls. Milk samples for P4assay were collected after parturition every 3 days until P4 concentration in the milk of the goats leaped beyond 1.5 ng/ml. Injection of PGF2α on day 7 p.p. had no effect (p>0.05) on the PPI. However, PGF2αinjections on day 15 and day 21 p.p. significantly (p<0.0I, P<0.00l) reduced the PPI by 18 and 30 days, respectively. The P4 level of goats treated with PGF2α on day 7, 15, and 21 p.p. remained below 0.04 ng/ml until days 51, 43, 30 p.p. respectively, then increased to a level ≥1.0 ng/ml. The P4 profile of the control goats remained below 0.04 ng/ml until day 61 p.p and started to increase to a level ≥1.0 ng/ml on day 67. Experiment II investigated the effects of GnRH injection during early p.p on the PPI and P4profile of the Nubian goats. Twenty p.p Nubian goats were distributed to 4 groups. Group I (n = 5) was i.m injected with 100 µg of GnRH on day 7 p.p, group II (n = 5) was injected on day 15 p.p and Group III (n = 5) was injected on day 21 p.p. Group IV (n = 5) was not injected and served as controls. GnRH injection on day 7, 15, and 21 p.p. significantly (p<0.05, p<0.0I, P<0.00I) reduced the PPI by 32.8, 40.8, 41.8 days, respectively. The P4 levels of goats treated with GnRH on day 7, 15, and 21 p.p remained below 0.04 ng/ml until days 36, 28, 27 p.p, respectively, and then it increased to levels ≥1.0 ng/ml. The P4of the control group remained at a basal level of 0.04 ng/ml until day 68 p.p. and then increased to level ≥ 1.0 ng/ml. It is concluded that p.p Nubian goats treated with PGF2α or GnRH during early p.p resume ovarian activity earlier than non treated control. Thus their PPI was reduced.
[Adil Salim Elsheikh , Nawal Nour Eldaim Ome, Abdulrahman Mohamed Alqurashi. Management of Postpartum Interval of Nubian goats with PGF2α and GnRH. J Am Sci 2013;9(3):181-184] (ISSN: 1545-1003). http://www.jofamericanscience.org. 23
Key words: Postpartum interval, Nubian goats, PGF2α, GnRH. Full Text 23