Medical Genetics








Medical Genetics Questions


I- Match the sentences from group I with the appropriate from group II.

Column I

Column II

1. Multiplication Rule In Genetics

2. Phenotype

3. Homozygote

4. Genotype

5. Allele

6. Heterozygote

7. Locus

8. The Punnett Squar

9. Alkaptonuria

10. Addition Rule In Genetics



Ø (….) An individual possessing two different alleles at a locus

Ø (….) One of two or more alternate forms of a gene

Ø (….) An individual possessing two of the same alleles at a locus

Ø (….) Specific place on a chromosome occupied by an allele

Ø (….) Is a short-hand method of predicting the genotypic and phenotypic

ratios of progeny from a genetic cross.

Ø (….) Patients who produced black urine (Voiding black urine).

Ø (….) Set of alleles that an individual possesses

Ø (….) Refers to the actual Physical appearance of an individual.

Ø (….) States that the probability that any one of two or more mutually exclusive events occurring is calculated by adding their probabilities.

Ø (….) States that the probability of two or more independent events occurring together is calculated by multiplying their independent probabilities.

II- Choose the correct answer  (put underline)?

1. The two alleles of an individual cell separate with (unequal probability - equal probability – different probability) into the gametes.

2. When dominant and recessive alleles are present together, the recessive allele is (present – masked – moderate).

3. When a trait displays (codominance - complete dominance - incomplete dominance), the genotypic ratios and phenotypic ratios of the offspring are the same.

4. When a trait exhibits incomplete dominance, a cross between two heterozygotes produces a (9:3:3:1   -   1:2:1   –   3:1   –   1:1) phenotypic ratio in the progeny.

5. If we examined 42 people having an allele for polydactyly and found that only 38 of them were polydactylous, the penetrance would be equal to (0%   -   50%   -   90%   -   100%).

6. When the genotype consists of a dominant and a recessive allele, the phenotype will be like (The Dominant - The Recessive - Neither) allele.


7. If two people who are both carriers for a genetically inherited fatal recessive disease decide to become parents, what will be the odds that their children will also be carriers?



a) 1 out of 4

b) 2 out of 4

c) 3 out of 4

d) 4 out of 4



8. If a woman is homozygous normal and her husband is heterozygous for a genetically inherited recessive disease and they decide to become parents, what is the probability that they will have a healthy child?


a) 1 out of 4

b) 2 out of 4

c) 3 out of 4

d) 4 out of 4



9. Punnett squares are used by geneticists to determine the probability of different offspring genotypes. In the one shown below, what letter(s) belong in the lower right box?


a) Aa

b) AA

c) aa

d) aA

  1. Assuming that both parent plants in the diagram below are homozygous, why would all of the f1 generation have yellow phenotypes?


a) Because the F1 genotypes are homozygous

b) Because yellow is dominant over green

c) Because both parents passed on yellow alleles

d) Because green is dominant over yellow

III- Fill the withe correct words or expressions:

1. Gene is a region of DNA that helps determine a characteristic

  1. The Punnett squar          e is a short-hand method of predicting the genotypic and phenotypic ratios of progeny from a genetic cross.
  2. Patients who produced black urine (Voiding black urine) is, a condition known as alkaptonuria
  3. In testcross, one individual of unknown genotype is crossed with another individual with a homozygous recessive     e genotype for the trait in question.
  4. Incomplete penetrance and variable expressivity result from the influence of other gene  s and environmental factors on the phenotype.


IV- On genetic basis answer Two the following questions?

1.Albinism, a recessive condition in humans that causes reduced pigmentation in the skin, hair, and eyes. When two parents heterozygous for albinism mate (Aa X Aa), use abinomial expansion find the probability of this couple having Seven children?

a) Two with albinism and Five with normal pigmentation

b) Four with albinism and Three with normal pigmentation

2- In a family of Five children, what is the probability of obtaining the following numbers of boys and girls?

(a) All boys

(b) All children of the same sex

(c) Six girls and one boy

3- In humans, alkaptonuria is a  Phenylketonuria (PKU) is a disease that results from a recessive gene. Two normal parents produce a child with PKU.

(a) What is the probability that a sperm from the father will contain the PKU allele?

(b) What is the probability that their next child will be heterozygous for the PKU gene?

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الساعات المكتبية

الأحـد 10-2 * الأثنين 12-3 * الثلاثاء 11-2

أعلانات : أختبــــارااااااات

First Mid-Term Examination Schedule - Second Semester 1435-1436

Day

Date

Course Name

Code & Number

Wednesday

13 / 5 / 1436

Medical Genetics

MDL 322

Thursday

14 / 5 / 1436

Histology

MDL 211

MDL 242

Monday

18 / 5 / 1436

Hematology

MDL 311

MDL 241

Tuesday

19 / 5 / 1436

Electron Microscope

MDL 314

MDL 362


ترقبو ا حدول أختبارات أعمال السنة الثاني ... قريبا

Second Mid-Term Examination Schedule Second Semester 1435-1436

مقالاتي: انت دمك خفيف

1- انت دمك خفيف!!!

كن متميزا

كيف تتفوق ...  هل فكرت يوما أن تعرف أسرار التفوق من أصحاب التفوق أي من الأوائل أنفسهم من أسرار التفوق مايلي :-

شاهد العلم

التقويم : اليوم والساعة

إحصائية الموقع

عدد الصفحات: 45

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الزيارات: 135951