Breast
Breast Cancer Risk Factors among Women without Family
History in North West of Iran
Ali Pourzand 1,
Homa Farajkhah 2, Ramin Azhough 1, Mohammad
Bassir Abolghassemi Fakhree 1
1. Department of General Surgery, Imam Reza
Hospital, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz,
Iran
2. Faculty of Medicine, Tabriz University of
Medical Sciences, Tabriz, Iran
Abstract: Breast
cancer is the most common cancer among Iranian women. This study aimed to
investigate risk factors for non-familial breast cancer in the northwest of
Iran. A case-control study was conducted from March 2010 to March 2012 in
Tabriz, Iran. Two hundred women with breast cancer and 200 age-matched healthy
women were included. Demographical data and risk factor related information
were collected using a short structured questionnaire. Statistical analysis was
carried out using conditional logistic regression with the forward elimination
method and odds ratios (ORs) with related 95% confidence intervals (CIs) were estimated.
The mean ± SD ages of cases and controls were 50.05±11.47 and 49.91±11.83
years, respectively. Multivariate analysis showed that low to moderate
socioeconomic status (OR=6.19, 95%CI: 2.92-13.11), previous genital surgery
(OR=3.97, 95%CI: 1.53-10.33) and no history of miscarriage (OR=2.41, 95%CI:
1.14-5.09) were risk factors for breast cancer. These findings indicate that
low to moderate socioeconomic status, previous genital surgery and no history
of miscarriage are factors significantly associated with increased breast
cancer risk among Iranian women within Northwest of Iran.
[Pourzand
A, Farajkhah H, Azhough R, Fakhree MB. Breast Cancer Risk Factors among
Women without Family History in North West of Iran. Life
Sci J 2013;10(7s):482-489]. (ISSN:1097-8135). http://www.lifesciencesite.com. 75
Keywords: Breast cancer; case-control study; risk factors;
Iranian women
