Remedi
Remedial Effect of Cinnamon Zeylanicum on
serum anti-oxidants levels in male diabetic Rat
Arash Khaki1, Roshanak
Bayatmakoo2*, Mohammad Nouri1, Amir Afshin Khaki1
1. Women’s
Reproductive Health Research Center, Tabriz University of Medical Sciences,
Tabriz, Iran
2. Department
of Biochemistry, Tabriz Branch, Islamic Azad University, Tabriz, Iran
*Corresponding
author: [email protected]
Abstract: Cinnamon
is an antioxidant and it has been shown to reduce oxidative stress. Previous
study confirmed antioxidants enzymes have imbalanced on diabetes by
hyperglycemia role on reactive oxygen’s spaces and is one of the male
infertility agents. Wistar male rat (n=40) were allocated into four groups,
control group (n=10) , Cinnamon group that received 75mg/kg by gavage method,
diabetic group and diabetic group that treatment Cinnamon 75mg/kg daily
for 30 days respectively ,however the control group just received an
equal volume of distilled water daily. In 30day, 5 cc blood sample of
each rat was taken for anti-oxidants measurement. serum catalase, Superoxide
dismutase and Glutathione peroxidase levels
significantly were increased in group that has received 75mg/kg Cinnamon in
comparison to control and diabetic groups (P<0.05). Serum
malondialdehyde level significantly was decreased in group that has
received 75mg/kg Cinnamon in comparison to control and diabetic
groups (P<0.05).Since in our study 75mg/kg Cinnamon has significantly
increased serum anti-oxidants levels so it seems using it in diabetic
male patients has beneficial effects.
[Arash
Khaki, Roshanak Bayatmakoo, Mohammad Nouri, Amir Afshin Khaki. Remedial
Effect of Cinnamon Zeylanicumon serum anti-oxidants levels in male
diabetic Rat. Life Sci J 2013;10(4s):103-107] (ISSN:
1097-8135).http://www.lifesciencesite.com. 15
Keywords: Antioxidant,
CAT, Cinnamon, GPX, infertility, MDA, SOD.
