A prospe
A
prospective study of Green Tea and panax Ginseng against mutagens &
carcinogens produced during Thermolyzed Meat and Fish
Osfor, M. M. H.; A. El-Ashi;
M. El-Madbouly; Mona. S. zaki*; and Doaa Negm
Department of Clinical
Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi
Arabia
* 'Department of
Hydrobiology, National Research Center. Cairo, Egypt
Abstract: Effect
of thermolyzed (ultra heated) Meat and fish on the nutritional, biochemical,
histological, and hematological parameters as well as aberrations and sperm
abnormalities was investigated in male albino rats. Animals were divided into
two main groups: Meat group and Fish group. Each group was divides into six
subgroups: G-I was fed the basal diet containing more than 12% dry frozen meat,
G-II & G-III were fed the basal diet of G-I plus 5% of Green Tea and Panax
Ginseng respectively. G-IV was fed the basal diet containing more than 12% Thermolyzed
Meat, while, G-V & G-VI were fed the basal diet of G-IV plus 5% of Green
Tea and Panax ginseng respectively. The same classification was done for the
fish groups. It was found that the terminal body weight was increased
non-significantly in all rat groups until the fifth week, and then decreased
non-significantly until the end of the experimental periods (8 weeks). No
effect on serum cholesterol, triglycerides, total lipids and glucose levels was
found. On the other hand, significant values of both hepatic and renal function
parameters were obtained among ultra heated meat and fish treated animals.
Numerous histological alterations, particularly in the liver, were also
observed. Moreover, anemia, leukocytosis, neutophilia, lymphocytosis and
monocytosis were seen. Furthermore, chromosomes and sperms were adversely
affected in such animals fed diet contained ultra heated meat and fish. The
protective role of green tea and panax ginseng were observed in all
biochemical, histological, and hematological parameters. In addition,
improvement in chromosomal aberration and sperm abnormalities was also noticed.
[Osfor, M. M. H.; A. El-Ashi; M. El-Madbouly; Mona. S. zaki; and Doaa Negm. A prospective study of Green Tea and panax Ginseng against mutagens & carcinogens produced during Thermolyzed Meat and Fish. Life Sci J 2013;10(1):1754-1765]. (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Ultra heated meat and fish, Green Tea, Panax ginseng, Albino rats.
