Antioxid
Antioxidant
and anticancer activities of water and ethanol extracts obtained from Sasa quelpaertensis Nakai
Ji Young Kim §,1,
Jung Hyun Kim §,2, Ji Hee Byun §,1,
Ji Hye Kim 1, Youn Ji Lee 1, Soon Jae
Im 1, Dong-Sun Lee 1,4, Seo
Hyun Moon 3, Min Young Kim 1,4,*
1. Laboratory
of Pharmacology and Toxicology, Faculty of Biotechnology, College of Applied
Life Science,Jeju National University, Jeju 690-756, Republic of Korea
2. Department of Tourism and Food Service Cuisine, Cheju
Tourism College, Jeju 695-900, Republic of Korea
3. DNA Forensic Center, National Forensic Service, Seoul
158-707, Republic of Korea
4. Subtropical
Horticulture Research Institute, Jeju National University, Jeju 690-756,
Republic of Korea
§. Contributed
equally
Abstract: Antioxidant
activities of Sasa quelpaertensis Nakai leaf extracts using
two different solvents (water and ethanol) were determined by using in
vitro antioxidant models including 1,1-diphenyl-2-picrylhydrazyl(DPPH)
radical, hydrogen peroxide and nitric oxide scavenging activities, and
ferrous chelating and reducing power activities. Both extracts were shown
to be antioxidants; however, ethanol extract exhibited higher antioxidant
activity than that of water extract. The total phenolic and flavonoid
contents of Sasa quelpaertensis Nakai leaf extract was
positively correlated with the antioxidant activity. Significantly, the
ethanol extract exerted the most potent cytotoxicity activity against human
colon cancer HCT116 cells.
[Ji Young Kim, Jung Hyun
Kim, Ji Hee Byun, Ji Hye Kim, Youn Ji Lee, Soon Jae Im, Dong-Sun
Lee, Seo Hyun Moon, Min Young Kim. Antioxidant and anticancer
activities of water and ethanol extracts obtained fromSasa quelpaertensis Nakai. Life Sci J 2013;10(1):1250-1254] (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Sasa quelpaertensis Nakai; antioxidant and anticancer potentials