The Risk
The Risk Probability of Fasting Ramadan for Patients
with CABG
Ahmed Samy1, Moshira
H. Sabry 2, Abdelhady M. Hamada 2 and
Osama Rifaie 3
1Cardiothoracic Surgery, 2Clinical and
Chemical Pathology, 3Cardiology Cardiothoracic Surgery
Department & Cardiology Department; Faculty of Medicine, Ain Shams
University
Abstract: The effect of Fasting Ramadan on high risk patients
with coronary artery disease (CAD) who had coronary artery bypass grafting
(CABG) is a difficult question to answer. Some doctors advise these patients to
break fasting, but many patients keep fasting with no medical problems or if
present not recorded. Patients with CABG who persist to fast Ramadan give us
the opportunity to do our study. We studied 42 patients as regard the effect of
Ramadan fast on their clinical status including chest pain (angina), blood
pressure, cardiac enzymes, ECG and echocardiography. We also, study the effect
of fasting on serum cholesterol, triglycerides and Malondialdehyde (MDA) as the
end product of lipid peroxidation, Ultrasensitive CRP (Hs-CRP) as a predictive
value of the inflammatory process and the osmolarity of the blood during
fasting and compared to the non-fasting. The results showed three patients
developed chest pain on day 17, 20, 24 of fasting due to chest infection and
pleurisy with no other abnormalities detected. Two other patients developed
elevated systolic blood pressure due to stoppage of diuretics without
replacement with other drug during fasting. Two patients of the cigarette
smokers were frequently complained of chest pain before fasting they become
symptoms free during fasting which may be due to cessation of smoking which was
of great benefit for these patients to release this risk factor. There
was significant decrease of Hs-CRP during fasting which reflects improvement of
the inflammatory process thus releasing one of the risk factors for CAD. There
was no significant difference between fasting and non-fasting cholesterol and
triglycerides levels. MDA showed significant increase during fasting reflecting
increased lipid peroxidation. There was also sig increased osmolarity during
fasting with hem concentration. We conclude that the patient can fast Ramadan
safely with proper medical supervision for control of hypertension and if
diuretic was withdrawn it must be replaced with other modality of treatment
during fasting with proper hydration. Also, the patient must take
anti-oxidant during fasting.
[Ahmed Samy, Moshira H. Sabry, Abdelhady M.
Hamada and Osama Rifaie. The Risk Probability of Fasting Ramadan
for Patients with CABG. Life Sci J 2013;10(1):354-359].
(ISSN: 1097-8135).http://www.lifesciencesite.com. 57
Key
Words: Malondialdehyde (MDA),
CAPG, Hs-CRP, Ramadan fasting Full Text 57
