Clostridium
Clostridium perfringens Disease
1Nagwa, Ata, 1Eman A. Khairy ,1Sohad
M. Dorgham and 2Mona S, Zaki
1Dept.Microbiology and immunology, National Research
Centre, Giza, Egypt
2Dept.Hydrobiology, National Research Centre, Giza,
Egypt
dr_mona [email protected]
Abstract: C. perfringens (Clostridium perfringens) is
a pathogen whose infects human and animals. In spite of its potential danger as
an infectious agent, avirulent forms of bacillus can be found in many different
habitats, such as the normal flora of human gastrointestinal (GI) tract, and
environment, such as sewage and soil. Several common diseases associated
with C. perfringens were recorded such as food-poisoning, gas
gangrene, necrotic enteritis and many veterinary diseases. The trouble starts
when the balance of bacteria in the gut is disrupted, giving C.
perfringens a chance to proliferate unchecked. It may contaminate soil,
animal feed and litter, or be transmitted directly from infected to healthy
animals. C. perfringens related livestock infections have been reported in
most parts of the world. Once an animal
contracts a disease caused by C. perfringens it’s often too late to do
anything about it, Death comes quickly and violently. The most
practical way to handle perfringens-related illnesses in animals is to prevent
them in the first place. The present literature review of the diagnosis, type
determination of major lethal toxins and diseases caused by C. perfringens.
[Nagwa, Ata, Eman A. Khairy, Sohad M.
Dorgham and Mona S, Zaki. Clostridium perfringens Disease. Life
Sci J 2013;10(1):1599-1602] (ISSN: 1097-8135). http://www.lifesciencesite.com.
Keywords: Key words: C. perfringens; C. perfringens toxins; food poisoning; necrotic enteritis.