Studies on H
Studies on Hematological Parameters and DNA Structure in Newborn Rats Exposed to Extremely Low Frequency Magnetic Fields
Nihal S. El-Bialy, Reem H. El-Gebaly* and Monira M. Rageh
Department of Biophysics, Faculty of Science, Cairo University, Egypt. [email protected]
Abstract: The aim of this study was to evaluate the possible effects of in vivo exposure to extremely low frequency magnetic fields (ELF-MF) on some hematological parameters, pathological variations and DNA structure in newborn rats. Six female pregnant Wistar rats were obtained from the National Research centre in Egypt and gave birth to 30 rats at the animal house of Cairo University. The newborn rats were divided into two separate groups: one exposed group (50 Hz, 0.5 mT, 30 days, 24 h/day) and one control (sham). Red blood cells (RBCs), hemoglobin and hematocrit levels decreased significantly (P< 0.02) while white blood cells (WBCs) and platelets levels significantly increased ( P< 0.04) in newborn rats that were exposed to ELF-MF. There was no significant difference in mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV) levels and DNA structure between the exposed and sham-exposed groups. ELF-MF induced a marked necro-degenerative change in kidney tissue and peri-portal fibrosis in liver tissues. Our results indicate that the applied ELF-MF exposure may induce statistically significant alterations in some hematological parameters, kidney and liver tissues of newborn rats.
[Nihal S. El-Bialy, Reem H. El-Gebaly and Monira M. Rageh. Studies on Hematological Parameters and DNA Structure in Newborn Rats Exposed to Extremely Low Frequency Magnetic Fields. Life Sci J 2012;9(1):489-495]. (ISSN: 1097-8135).http://www.lifesciencesite.com. 74
Key Words: Electromagnetic field, hematological parameters, DNA, pathological tissues. Full Text 74
