Psychiatric Morb
Psychiatric
Morbidity and Glycemic Control in Type 2 Non Obese Diabetic Egyptian Patients
Tawfik El Adl 1,
Ashraf Talaat 1,Osman Elsayed 2,Mohamed Shahda 3and
Mostafa Neamatallah4
Internal Medicine Department1,Benha
University; Psychiatry Department2,Suez Canal University; Psychiatry
Department3,Mansoura University; Medical Biochemistry Department4,Mansoura
University; Egypt.
Abstract: Context: Type 2 diabetes mellitus doubles the odds of suffering
from depressive illness. Objectives:The present prospective
randomized controlled study aimed to estimate the prevalence of anxiety and
depressive disorders among a consecutive group of patients with type 2 non
obese diabetes and assess its impact on glycemic control. Subjects and
Methods: We selected 200 consecutive adult patients with type 2 non
obese diabetes mellitus. Patients were divided into 2 groups according to HbA1c
level: >7% defined group1 with poor glycemic control (n=140) and ≤7%
defined group2 with good glycemic control (n=60). All patients were assessed
using semi structured Sociodemographic data form, Hospital Anxiety Depression
Scale, The Mini Mental State Examination and Mini international
Neuropsychiatric Interview (MINI). Results: Anxiety and
depressive scores (HAD) were significantly higher in group 1 patients than in
group 2 .The prevalence rate of psychiatric disorders were as follow: major
depressive disorders 30.7%, dysthymic disorders 15.7% generalized anxiety
disorder 10.7%, panic disorder with or without agoraphobia 10%, social anxiety
disorder10%, obsessive compulsive disorder 5.7%, post traumatic stress disorder
5(3.6%) in group1 patients and major depressive disorder 18.3%, dysthymic
disorder 11.7%, generalized anxiety disorder 8.3%,panic disorder with or
without agoraphobia 6.7% social anxiety disorder 6.7%, obsessive compulsive
disorder 5%, post traumatic stress disorder 3.3% in group2 patients
.Correlation coefficient were computed among hospital anxiety depressive scores
(HAD) and HbA1c level, where significant positive correlation was found between
these scores and HbA1c level in the diabetic patients indicating the negative
impact of depressive and anxiety disorders on glycemic control among
diabetics. Conclusion: Anxiety and depressive disorders were
significantly more frequent in patients with poor glycemic control (more than
one third) than in those with good glycemic control. There was a strong
association between HbA1c and depressive and anxiety symptoms. The presence of
depressive symptoms was associated with a significant worsening of glycemic
control.
[Tawfik
El Adl, Ashraf Talaat, Osman Elsayed, Mohammed Shahda and
Mostafa Neamatallah. Psychiatric Morbidity and Glycemic Control in Type
2 Non Obese Diabetic Egyptian Patients. Life Sci J 2013;10(1):1071-1078]
(ISSN:1097-8135). http://www.lifesciencesite.com.
Keywords: Psychiatric Morbidity,Glycemic Control,Diabetes.
