Antioxidant activ
Antioxidant activity of celery in vitro
and vivo
Amnah, M. A .Alsuhaibani
Nutrition and
Food Sciences Dept, Home Economic Collage, Princess Nora
Bint Abdul Rahman -University, Riyadh, Saudi Arabia. [email protected]
Abstract: The
objective of this work was to investigate the main antioxidant components of
celery and study the antioxidant effect of celery extract in vitro and in
vivo in rats. Oxidative stability of celery extract was determined by
estimation of peroxide value. Celery extract and BHT at level 400 ppm
effectively inhibited the increase in peroxide value especially for a period of
32 hrs of heating. Forty Sprague Dawley adult male rats classified
into control (-ve) and four groups which received 200 mg/kg body weight of potassium
bromate in drinking water for 30 days to induce renal injury and
reclassified into positive control (untreated) and treated rat groups that
werecelery powder, 2.5celery extract and 5 celery extract groups. Results
clearly revealed that 2.5 celery extract and 5 celery extract groups showed normal body weight gain, food intake, protein
intake and protein efficiency ratio but showed lower food
efficiency ratio compared to control (-ve)
rat group. Celery powder rat group
showed highly significant increase in serum creatinine, urea, ALT and nitric
oxide (NO) but showed significant lower in serum
antioxidant enzymes and also kidney superoxide dismutase (SOD), compared to control (-ve) rat group.2.5celery
extract group showed significant lower in
SOD and GPX while 2.5 celery extract and 5 celery extractgroups showed normal in renal function0 parameters and
the values of kidney antioxidant enzymes compared to control (-ve) rat group.
[Amnah, M. A
.Alsuhaibani. Antioxidant activity of celery in vitro and vivo. J
Am Sci 2013;9(6):459-465]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 57
Keywords: Celery - BHT- potassium bromate - rats. Full Text 57
