Correlation betwe
Correlation between body mass
index (BMI) and immunologic Response to Hepatitis B Vaccine
Mojtaba
Varshochi and Sepehr Taghizadeh
Infectious
Diseases and Tropical Medicine Research Center, Faculty of medicine,
Tabriz University of Medical Sciences, Tabriz, Iran. v[email protected]
Abstract: Problem statement: To evaluation the
Correlation between body mass index (BMI) and immunologic Response to Hepatitis
B Vaccine. Methods: In a cross sectional descriptive analytic study carried out
on the health care Workers (HCWs) of Tabriz Shahid Madani Hospital in
20010-2011, we evaluated the immunologic response of the staff to vaccination
against Hepatitis B and correlation by body mass index (BMI). Results and
Conclusion: Results: 122 people (36.8%) from the studied HCWs were male and 209
people (63.2%) female. The mean Primary and secondary antibody titer in the
studied HCWs were 304.07±199.98 and 369.13 ± 169.78 IU/L. From 331
studied people, 31 (9.4%) showed no response to vaccination, 52 (15.7%) low
response and 248 (74.9%) good response and after one booster dose, 7 (2.1%)
showed no response to vaccination, 5 (1.5%) low response and 319 (96.4%) good
response. In our study, the response rate to the vaccine has been reduced by
increased weight and BMI, although this reduction was not statistically
significant. Mean of Primary response antibody titer in male was significantly
higher than female HCWs(P=0.011).Significant liner correlation was not found
between HBsAb level and HCWs weight and BMI.
[Varshochi M, Taghizadeh S. Correlation between
body mass index (BMI) and immunologic Response to Hepatitis B Vaccine. Life Sci J 2013;10(1):210-213]
(ISSN:1097-8135). http://www.lifesciencesite.com. 31
Keywords: Hepatitis B Vaccines; Occupational
Diseases; BMI; Immunologic Response Full Text 31
