Histological chang
Histological changes of Mice lungs after daily exposure
to different concentration of Incense smoke
Samar Omar
A. Rabah1, Sahar Ragab El Hadad1,2 and Fatmah Albani.1
1Biology Department, Faculty of Science, King Abdulaziz
University, Jeddah, KSA
2Genetic Engineering Research and Bioinformatics
Center, VACSERA, Egypt
Abstract: Since
the discovery of Agarwood (Incense tree), many studies reported its
characteristic effects and variable benefits, as either to produce Arabian
Incense or as a traditional medicine against many diseases. Laboratory experiments
were carried out on the effect of different concentrations of Incense smoke
inhalation on the lung weight and tissue in female mice. This research derives its importance from the fact that Incense
is heavily used in Saudi Arabia in the absence of thorough studies of its
effects on health. Eighty animals areused in
this study, and are divided into four
groups, each is 20 animals. Three groups
are exposed to different concentrations (2,
4 and 6 gm) of Incense smoke daily for three
months, and the fourth group is the control.
At the end of each month, five animals from each group were dissected.
Obtained data showed an increase but not significant in animal body and lung
weight, this results return to natural increase as a result of normal growth of
animals. Light microscope reveals some changes in the lung tissue, such as
focal emphysema, rupture in the alveolar walls, hemorrhage, congestion, edema
and few peri-bronchial lymphoid cells. After continuous exposure to Incense
smoke focal necrosis and degradation are observed in some cells of epithelial
bronchioles. Also, fibrosis of peri-bronchial, thickening in alveolar walls and
aggregation of lymphoid cells are demonstrated in some lungs sections .
Conclusion: according to the above manifestations it could be concluded that
exposure to Incense smoke causes pulmonary harmful effects. Therefore, we can
recommend that Incense smoke will be used only in open places to reduce its
harms.
[Samar Omar A. Rabah,
Sahar Ragab El Hadad and Fatmah Albani. Histological
changes of Mice lungs after daily exposure to different concentration of
Incense smoke. Life Sci J 2013;10(1):552-560].
(ISSN: 1097-8135).http://www.lifesciencesite.com. 90
Keywords: Incense smoke, lungs, histological changes
of lungs, Agarwood Full Text 90
