السيرة الذاتية

Curriculum Vitae

Dr. Raid Saleem Al-Baradie,PhD

Contact Details:

Kingdom of Saudi Arabia

Majmaah University

P.O. Box 1405

Almajmaah  11952

Tel: +96664042822

Fax: +96664042955

Mobile: +966553214222

+966509868968

Email: [email protected]

United Kingdom & Ireland (UK)

Home: 562 Princess Road, Chorlton, Manchester M21 7QA

Tel (Home): +44161 8618307

Mobile: +447879684145

+447737384707

Email: [email protected]

[email protected]

Education:

  • Post-doctoral Fellowship at Manchester Metropolitan University United Kingdom Manchester (2009-2010).
  • PhD Student on Manchester University Faculty of Medicine and human Sciences Department of pathology United Kingdom Manchester (2004-2008).
  • High Diploma on Molecular Experimental Techniques in theResearchCenteratDuke University Medical School,North Carolina,USAfor one year and three months (1997-1999).
  • BSc: ClinicalLaboratory Sciences Program Full Time King Saudi UniversitySaudi ArabiaRiyadh(1988-1993).
  • High School: Manarate Al-Riyadh School (1976-1988).

Work experience:

  • Vice Dean- College of Applied Medical Sciences, Majmaah University (2010-till now).
  • Post-doctoral fellowship at Manchester Metropolitan University United Kingdom Manchester (2009-2010).
  • PhD student in Manchester university faculty of Medicine and human sciences department of pathology and the name of the PhD project is the role of hyaluronan in cancer therapy since September (2004-2008).
  • Research Assistants in the Department of tumour immunology in the Research Centre of King Faisal Specialist Hospital From 2002 to 2005.
  • Research Technologist in the Department of Molecular Experimental Pathology, in theResearchCentre ofKingFaisalSpecialistHospital(1999-2002).
  • Research Assistants in Advanced in Molecular Experimental Techniques in the Research Center at Duke University Medical School, North Carolina, USA for one year and three months (1997-1999).
  • Histotechnologist in Pathology Department of King Faisal specialist Hospital (1996-1998).
  • Internships in Clinical Laboratory Practice at King Khalid University Hospital (1994-1995) and at King Fahad Hospital (1995-1996). The practice of all field of clinical laboratory including: Haematology, Biochemistry, Microbiology, Histology, Cytology, Blood Bank, Parasitology, Immunology, Serology, Virology and Mycology.

Memberships:

1. Saudi Heart Association

2. Saudi Pharmaceutical Association

3. Saudi  Stroke Association

Licenses:

1. Basic Life Support (BLS)

2. Advance life support (ACLS)

Research interests:

Signaling properties of hyaluronan

Anti-angiogenic properties of Opticin/Glycation of proteins in diabetes mellitus

Angiogenesis and neuroprotection after ischaemic stroke

Gene and protein de-regulation associated with angiogenesis in atherosclerosis

Achievements:

Post Doctoral Fellowship at Manchester Metropolitan University United Kingdom Manchester:

In my Post-doctoral fellow, my primary aim was to establish myself in the highly competitive fields of angiogenesis, stroke and cancer research.

Whilst at MMU, I have been involved in both undergraduate and post-graduate teaching in the areas of Biochemistry, Medical Laboratory Sciences, Genetics and the MSc taught course.

My work with Prof. Mark Slevin is primarily focused on the role of angiogenesis (the growth of new blood vessels) in (1) progression of atherosclerosis, (2) the pathophysiology of ischaemic stroke, (3) diabetic retinopathy, and (4) development of cancer. The work is of relevance to the public health sector, where these diseases account for a large proportion of mortality associated with ageing. I have identified and then examined in detail the anti-angiogenic effects of opticin, and its role in the development of proliferative diabetic retinopathy. This work has been supported by Diabetes UK. I also work on angiogenesis and revascularization after stroke involves examination of the role of cyclin-dependent kinase-5. I have been investigating in my post doctoral fellowship the mechanisms of induction of plaque angiogenesis. I have used both gene and protein microarrays to identify novel de-regulated molecules in complicated, unstable angiogenic regions of carotid plaques.

Duties and accomplishment as Hospital Histotechnologist, in the Pathology Department of King Faisal Specialist Hospital Research Center in Riyadh Saudi Arabia:

  1. Performed routine paraffin block sectioning from 1 to 5 micrometers.
  2. Performed routine Haematoxylin and Eosin staining of tissue sections.
  3. Performed over 40 Histology (special stain) in tissue sections and smears.
  4. Performed frozen section of tissues for urgent intra-operative diagnosis.
  5. Processed, embedded, sectioned and stained tissues for light microscopy.
  6. Cut and stained kidney biopsies (1 micron) including special stains such as Jones, PAS and mason Trichome.
  7. Trained internship students in the hospital in routine histology.
  8. Completed a course of Medical Terminology.
  9. Assisted pathologists in grossing area.
  10. Received and entered specimens into computer.
  11. Received Training in Molecular Biology techniques.

High Diploma on Research fellowship at Duke University Medical School, North Carolina, USA:

  1. Performed Immunohistochemistry techniques with different antibodies on frozen sections of tissues.
  2. Performed fluorescence in situ hybridization on paraffin sections and cell suspensions.
  3. Learned the basic techniques for Immunohistochemistry and conducted an independent project using the 81-c6 antibody on oligodendrogliomas.
  4. Learned the basic techniques of fluorescence in situ hybridization on paraffin sections and conducted an independent project studding c-myc amplification in medulloblastomas in paraffin sections.
  5. Learned the basic techniques for DNA purification and conducted an independent project using yac DNA for FFISH analysis to detect LOH oligodendrogliomas (LP, Iaq) and medulloblastoma (aQ).
  6. Learned the basic technique for DNA extraction from tissue and conducted an independent project on medulloblastoma. Samples were analyzed by DNA agarose gel electrophoresis.
  7. Trained in the basic theory and techniques or in situ hybridization for mRNA using radioactive probes and silver staining.
  8. Trained at Ventana Nexas Medical system Inc. inTusan,Arizonafor one month. Gained experience of their automated platform for immunohistochemistry staining.
  9. Performed immunofluorescence (IF) in frozen section in skin and kidney biopsies.

Duties and accomplishment as Research Assistants in the Molecular Experimental pathology and Tumour immunology Departments at Research Centre in King Faisal Specialist Hospital in Riyadh Saudi Arabia :

  1. Performed DNA extraction from Fresh and paraffin embedded tissues.
  2. Learned the basic techniques for lymphocytes harvest in peripheral blood and bone marrow and learn tissue culture techniques to grow T cell.
  3. Acted as liaison person between the Department of pathology and Research centre for many research projects by providing histological sections.
  4. Carried out PCR analysis for quality control of DNA in research centre.
  5. Gave lectures to staff in research centre in safety and Molecular techniques.
  6. Improved computer skills by undertook a six month courses in computer class.
  7. Finish many courses in Molecular biology and tissue culture.
  8. Work with many research projects that had been published including my name till now sex paper had been published including my name.

PUBLICATIONS


Krupinski J, Abudawood M, Matou-Nasri S, Al-Baradie R, Petcu EB, Justicia C, Planas A, Liu D, Rovira N, Grau-Slevin M, Secades J, Slevin M. (2012). Citicoline induces angiogenesis improving survival of vascular/human brain microvessel endothelial cells through pathways involving ERK1/2 and insulin receptor substrate-1. Vasc Cell. 2012 Dec 10;4(1):20. doi: 10.1186/2045-824X-4-20.


Slevin M, Badimon L, Matou S, Al-Baradie R, Krupinski J (2012). Increased Monomeric C-reactive Expression After Brain Damage may be Involved in Promotion of Vascular Pathology Including Alzheimer’s and Tumour Growth Austral - Asian Journal of Cancer ISSN-0972-2556, Vol. 11, No. 1, January 2012.

Slevin M, Badimon L, Matou S, Al-Baradie R, Krupinski J. (2011). Monomeric C-reactive Protein is Expressed in senile Plaques and microvessels in the Stroked brains of Patients with Alzheimer’s Disease Recent Advances and Research Updates. ISSN-0972-4699, Vol. 12, No.2, April 2011.

Al-Baradie, R., Matou, S., Gaffney, J., Slevin, M., Kumar, S. (2008). The role of hyaluronan in angiogenesis through RHAMM & CD44 receptors in human micro-vessel endothelial cells. Saudi International Innovation Conference 2008 SIIC2008, 1, 118-123.

Al-Baradie, R., Matou, S., Gaffney, J., Slevin, M., Kumar, S. (2009). The role of hyaluronan in angiogenesis through RHAMM & CD44 receptors in endothelial cells. Saudi International Innovation Conference 2009 SIIC2009, 1, 1-3

Al-Saleh, I., El-Doush, I., Shinwari, N., Al-Baradei, R., Khogali, F., Al-Amodi, M. (2005). Does low mercury containing skin-lightening cream (fair & lovely) affect the kidney, liver, and brain of female mice? Cutan Ocul Toxicol, 24, 11-29.

Al-Saleh, I., Khogali, F., Al-Amodi, M., El-Doush, I., Shinwari, N., Al-Baradei, R. (2003). Histopathological effects of mercury in skin-lightening cream. J. Environ Pathol Toxicol Oncol, 22, 287-299.

Bouchama, A., Roberts, G., Al Mohanna, F., El-Sayed, R., Lach, B., Chollet-Martin, S., Ollivier, V., Al Baradei, R., Loualich, A., Nakeeb, S., Eldali, A., de Prost D. (2005). Inflammatory, hemostatic, and clinical changes in a baboon experimental model for heatstroke. J. Appl Physiol, 98, 697-705.

McLendon, R., Wikstrand, CJ., Matthews, MR., Al-Baradei, R., Bigner, SH., Bigner, DD. (2000). Glioma-associated antigen expression in oligodendroglial neoplasms. Tenascin and epidermal growth factor receptor. J. Histochem Cytochem, 48, 1103-1110.

Zou, M., Al-Baradie, R., Al-Hindi, H., Farid, NR., Shi, Y. (2005). S100A4 (Mts1) gene over expression is associated with invasion and metastasis of papillary thyroid carcinoma. Br. J. Cancer, 93, 1277-1284.

الساعات المكتبية

السبت  والاثنين  


وايضا خلال فترة الصيف 

أعلان هام

لا يوجد شيء 

أرقام الاتصال

064042822

064042774

0553214222


التحويلة الداخلية : 

2822

2774





الساعات المكتبيه

الإثنين:  12 - 4

الأربعاء: 12 - 4

الخميس:  12 - 4


 


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